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Yoshinori Nozawa Selected Research

Leukemia

5/2020Vaticanol C, a phytoalexin, induces apoptosis of leukemia and cancer cells by modulating expression of multiple sphingolipid metabolic enzymes.
2/2016Resveratrol-induced transcriptional up-regulation of ASMase (SMPD1) of human leukemia and cancer cells.
1/2014Phosphorylated Sp1 is the regulator of DNA-PKcs and DNA ligase IV transcription of daunorubicin-resistant leukemia cell lines.
10/2010Chalcone glycosides isolated from aerial parts of Brassica rapa L. 'hidabeni' suppress antigen-stimulated degranulation in rat basophilic leukemia RBL-2H3 cells.
8/2010Phenolic constituents isolated from Fragaria ananassa Duch. inhibit antigen-stimulated degranulation through direct inhibition of spleen tyrosine kinase activation.
6/2010Inhibitory effects of whisky congeners on IgE-mediated degranulation in rat basophilic leukemia RBL-2H3 cells and passive cutaneous anaphylaxis reaction in mice.
8/2009Inhibitory effects of flavonoids isolated from Fragaria ananassa Duch on IgE-mediated degranulation in rat basophilic leukemia RBL-2H3.
4/2009Inhibitory effects of sesquiterpene lactones isolated from Eupatorium chinense L. on IgE-mediated degranulation in rat basophilic leukemia RBL-2H3 cells and passive cutaneous anaphylaxis reaction in mice.
4/2009Intracellular glutathione regulates sesquiterpene lactone-induced conversion of autophagy to apoptosis in human leukemia HL60 cells.
8/2008Inhibitory effects of polymethoxy flavones isolated from Citrus reticulate on degranulation in rat basophilic leukemia RBL-2H3: enhanced inhibition by their combination.
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Yoshinori Nozawa Research Topics

Disease

26Neoplasms (Cancer)
05/2020 - 06/2002
19Leukemia
05/2020 - 04/2003
15Prostatic Neoplasms (Prostate Cancer)
10/2016 - 06/2002
12Experimental Melanoma
10/2010 - 03/2003
8Colonic Neoplasms (Colon Cancer)
10/2015 - 01/2002
8Pheochromocytoma
06/2012 - 07/2002
8Neuroblastoma
11/2011 - 09/2004
7Diabetes Mellitus
03/2009 - 11/2006
6Myocardial Infarction
11/2011 - 10/2007
6Hypertension (High Blood Pressure)
05/2009 - 06/2007
5Atherosclerosis
03/2013 - 02/2007
4Neoplasm Metastasis (Metastasis)
10/2013 - 10/2007
4Obesity
03/2013 - 02/2007
4Ischemic Stroke
06/2010 - 11/2009
4Metabolic Syndrome (Dysmetabolic Syndrome X)
03/2009 - 02/2007
4Cerebral Infarction
08/2008 - 08/2006
4Hypercholesterolemia
06/2008 - 11/2006
3Breast Neoplasms (Breast Cancer)
06/2012 - 10/2007
3Mitochondrial Diseases (Mitochondrial Disease)
04/2009 - 11/2004
3Carcinogenesis
03/2008 - 02/2003
3Type 2 Diabetes Mellitus (MODY)
11/2007 - 08/2006
3Colorectal Neoplasms (Colorectal Cancer)
08/2007 - 02/2003
2Inflammation (Inflammations)
03/2013 - 07/2011
2Hepatocellular Carcinoma (Hepatoma)
03/2013 - 03/2002
2Hypersensitivity (Allergy)
07/2011 - 11/2009
2Chronic Renal Insufficiency
08/2009 - 03/2009
2Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage)
08/2008 - 08/2006
2Cerebral Hemorrhage
08/2008 - 08/2006

Drug/Important Bio-Agent (IBA)

12Pharmaceutical PreparationsIBA
05/2020 - 06/2002
12Proteins (Proteins, Gene)FDA Link
10/2015 - 12/2003
8Melanins (Melanin)IBA
10/2010 - 03/2003
7DNA (Deoxyribonucleic Acid)IBA
01/2014 - 01/2002
6Paclitaxel (Taxol)FDA LinkGeneric
10/2016 - 11/2007
6ResveratrolIBA
02/2016 - 01/2002
5vaticanol CIBA
05/2020 - 01/2002
5EnzymesIBA
05/2020 - 12/2003
5LipidsIBA
03/2013 - 10/2007
5Propolis (Bee Bread)IBA
10/2010 - 07/2003
4Messenger RNA (mRNA)IBA
10/2015 - 09/2009
4Hormones (Hormone)IBA
01/2012 - 06/2010
4Sirtuin 1IBA
01/2012 - 08/2008
4Apolipoproteins E (ApoE)IBA
05/2009 - 11/2006
4sphingosine kinaseIBA
04/2009 - 12/2003
4CamptothecinIBA
12/2008 - 06/2002
4Cytochrome P-450 CYP3AIBA
08/2008 - 11/2007
4XanthonesIBA
04/2008 - 08/2003
4mangostinIBA
03/2008 - 11/2004
3Glucose (Dextrose)FDA LinkGeneric
10/2015 - 01/2007
3taxaneIBA
10/2013 - 10/2010
3HydrogenIBA
03/2013 - 11/2009
3Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA
06/2012 - 04/2009
3CholesterolIBA
04/2012 - 02/2007
3ButyrophilinsIBA
11/2011 - 07/2011
3Immunoglobulin E (IgE)IBA
06/2010 - 04/2009
3CeramidesIBA
11/2009 - 06/2002
31-dodecylpyridoxal (PLD)IBA
09/2009 - 01/2004
3HDL CholesterolIBA
08/2009 - 10/2007
3LDL CholesterolIBA
08/2009 - 10/2007
3FlavonoidsIBA
08/2009 - 06/2006
3alpha-MSHIBA
06/2009 - 01/2004
3SesquiterpenesIBA
04/2009 - 02/2009
3LactonesIBA
04/2009 - 02/2009
3phospholipase D2IBA
03/2008 - 02/2003
3Biological ProductsIBA
03/2008 - 05/2005
3Monophenol Monooxygenase (Tyrosinase)IBA
10/2007 - 01/2004
3Caspase 3 (Caspase-3)IBA
01/2007 - 09/2003
32- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
04/2006 - 06/2002
2SphingolipidsIBA
05/2020 - 02/2016
2Phosphotransferases (Kinase)IBA
01/2020 - 12/2006
2Imatinib Mesylate (Gleevec)FDA Link
01/2020 - 09/2018
2Transcription Factors (Transcription Factor)IBA
10/2015 - 01/2014
2AndrogensIBA
10/2015 - 11/2007
2Daunorubicin (Cerubidine)FDA LinkGeneric
01/2014 - 11/2009
2Tretinoin (Retinoic Acid)FDA LinkGeneric
06/2012 - 01/2010
2Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA
11/2011 - 09/2007
2Reactive Oxygen Species (Oxygen Radicals)IBA
09/2011 - 02/2007
2sesaminIBA
03/2011 - 07/2009
2AntigensIBA
10/2010 - 08/2010
2cinnamic acidIBA
08/2010 - 06/2005
2Oligonucleotide ProbesIBA
06/2010 - 05/2010
2SuspensionsIBA
06/2010 - 05/2010
2LDL Lipoproteins (beta Lipoproteins)IBA
08/2009 - 10/2007
2Triglycerides (Triacylglycerol)IBA
08/2009 - 10/2007
2HDL LipoproteinsIBA
08/2009 - 10/2007
2thrombospondin 2IBA
03/2009 - 04/2007
2FlavonesIBA
08/2008 - 03/2008
2Adenosine Triphosphate (ATP)IBA
06/2008 - 11/2004
2Ethanol (Ethyl Alcohol)IBA
04/2008 - 05/2005
2beta-mangostinIBA
03/2008 - 11/2005
2Fluorouracil (Carac)FDA LinkGeneric
03/2008 - 08/2007
2Peptides (Polypeptides)IBA
11/2007 - 05/2005
2Uncoupling Protein 3IBA
10/2007 - 08/2006
2Thromboplastin (Tissue Factor)IBA
04/2007 - 08/2006
2Superoxides (Superoxide)IBA
02/2007 - 02/2007
2TunicamycinIBA
01/2007 - 10/2006
2Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
01/2007 - 09/2004
2Caspase 9IBA
01/2007 - 09/2004

Therapy/Procedure

7Therapeutics
04/2012 - 11/2005
4Drug Therapy (Chemotherapy)
10/2013 - 01/2006
2Stents
10/2007 - 10/2007